An analysis of data from electronic health records (EHRs) of almost 600,000 kids born in Kaiser Permanente hospitals in the region of southern California between the time period of 1991 and 2009 has discovered a link between complications soon before or during birth and a higher risk of a child establishing an autism spectrum disorder (ASD).
The research indicates the power of using EHRs to give data for medical research that could affect care delivery and lay the groundwork for additional analysis.
Of the 594,638 records analyzed, 6,255 kids were diagnosed with autism spectrum disorder; of those, 37% experienced perinatal complications, in accordance to the study, released in the American Journal of Perinatology.
These kids with complications during birth had a 10% higher risk of autism spectrum disorder, and that number increased to 22% if complications began before labor. In all, kids exposed to complications before and during birth had a 44% higher risk.
Complications with the highest risk of ASD involved birth asphyxia, premature separation of the placenta from the uterus, preeclampsia, breech/transverse fetal presentation, fetal dystocia/abnormal size or position, and a prolapsed/exposed umbilical cord, in accordance to study results.
“Our study recommends that kids exposed to certain perinatal complications, particularly birth asphyxia and preeclampsia, were more likely to be diagnosed with ASD than those who weren’t exposed, even after adjusting for factors like gestational age at birth and a mother’s age, race and education,” lead author Darios Getahun, MD, claims.
2 other Kaiser studies in the time period of 2014 and 2015 found siblings have fourteen times higher risk of establishing ASD if an older sibling has it, and children with mothers that developed gestational diabetes by the 26th week of pregnancy also confronted increased risk.
The most recent study is available here.
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